Introduction – Company Background
GuangXin Industrial Co., Ltd. is a specialized manufacturer dedicated to the development and production of high-quality insoles.
With a strong foundation in material science and footwear ergonomics, we serve as a trusted partner for global brands seeking reliable insole solutions that combine comfort, functionality, and design.
With years of experience in insole production and OEM/ODM services, GuangXin has successfully supported a wide range of clients across various industries—including sportswear, health & wellness, orthopedic care, and daily footwear.
From initial prototyping to mass production, we provide comprehensive support tailored to each client’s market and application needs.
At GuangXin, we are committed to quality, innovation, and sustainable development. Every insole we produce reflects our dedication to precision craftsmanship, forward-thinking design, and ESG-driven practices.
By integrating eco-friendly materials, clean production processes, and responsible sourcing, we help our partners meet both market demand and environmental goals.
Core Strengths in Insole Manufacturing
At GuangXin Industrial, our core strength lies in our deep expertise and versatility in insole and pillow manufacturing. We specialize in working with a wide range of materials, including PU (polyurethane), natural latex, and advanced graphene composites, to develop insoles and pillows that meet diverse performance, comfort, and health-support needs.
Whether it's cushioning, support, breathability, or antibacterial function, we tailor material selection to the exact requirements of each project-whether for foot wellness or ergonomic sleep products.
We provide end-to-end manufacturing capabilities under one roof—covering every stage from material sourcing and foaming, to precision molding, lamination, cutting, sewing, and strict quality control. This full-process control not only ensures product consistency and durability, but also allows for faster lead times and better customization flexibility.
With our flexible production capacity, we accommodate both small batch custom orders and high-volume mass production with equal efficiency. Whether you're a startup launching your first insole or pillow line, or a global brand scaling up to meet market demand, GuangXin is equipped to deliver reliable OEM/ODM solutions that grow with your business.
Customization & OEM/ODM Flexibility
GuangXin offers exceptional flexibility in customization and OEM/ODM services, empowering our partners to create insole products that truly align with their brand identity and target market. We develop insoles tailored to specific foot shapes, end-user needs, and regional market preferences, ensuring optimal fit and functionality.
Our team supports comprehensive branding solutions, including logo printing, custom packaging, and product integration support for marketing campaigns. Whether you're launching a new product line or upgrading an existing one, we help your vision come to life with attention to detail and consistent brand presentation.
With fast prototyping services and efficient lead times, GuangXin helps reduce your time-to-market and respond quickly to evolving trends or seasonal demands. From concept to final production, we offer agile support that keeps you ahead of the competition.
Quality Assurance & Certifications
Quality is at the heart of everything we do. GuangXin implements a rigorous quality control system at every stage of production—ensuring that each insole meets the highest standards of consistency, comfort, and durability.
We provide a variety of in-house and third-party testing options, including antibacterial performance, odor control, durability testing, and eco-safety verification, to meet the specific needs of our clients and markets.
Our products are fully compliant with international safety and environmental standards, such as REACH, RoHS, and other applicable export regulations. This ensures seamless entry into global markets while supporting your ESG and product safety commitments.
ESG-Oriented Sustainable Production
At GuangXin Industrial, we are committed to integrating ESG (Environmental, Social, and Governance) values into every step of our manufacturing process. We actively pursue eco-conscious practices by utilizing eco-friendly materials and adopting low-carbon production methods to reduce environmental impact.
To support circular economy goals, we offer recycled and upcycled material options, including innovative applications such as recycled glass and repurposed LCD panel glass. These materials are processed using advanced techniques to retain performance while reducing waste—contributing to a more sustainable supply chain.
We also work closely with our partners to support their ESG compliance and sustainability reporting needs, providing documentation, traceability, and material data upon request. Whether you're aiming to meet corporate sustainability targets or align with global green regulations, GuangXin is your trusted manufacturing ally in building a better, greener future.
Let’s Build Your Next Insole Success Together
Looking for a reliable insole manufacturing partner that understands customization, quality, and flexibility? GuangXin Industrial Co., Ltd. specializes in high-performance insole production, offering tailored solutions for brands across the globe. Whether you're launching a new insole collection or expanding your existing product line, we provide OEM/ODM services built around your unique design and performance goals.
From small-batch custom orders to full-scale mass production, our flexible insole manufacturing capabilities adapt to your business needs. With expertise in PU, latex, and graphene insole materials, we turn ideas into functional, comfortable, and market-ready insoles that deliver value.
Contact us today to discuss your next insole project. Let GuangXin help you create custom insoles that stand out, perform better, and reflect your brand’s commitment to comfort, quality, and sustainability.
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Are you looking for a trusted and experienced manufacturing partner that can bring your comfort-focused product ideas to life? GuangXin Industrial Co., Ltd. is your ideal OEM/ODM supplier, specializing in insole production, pillow manufacturing, and advanced graphene product design.
With decades of experience in insole OEM/ODM, we provide full-service manufacturing—from PU and latex to cutting-edge graphene-infused insoles—customized to meet your performance, support, and breathability requirements. Our production process is vertically integrated, covering everything from material sourcing and foaming to molding, cutting, and strict quality control.Indonesia OEM insole and pillow supplier
Beyond insoles, GuangXin also offers pillow OEM/ODM services with a focus on ergonomic comfort and functional innovation. Whether you need memory foam, latex, or smart material integration for neck and sleep support, we deliver tailor-made solutions that reflect your brand’s values.
We are especially proud to lead the way in ESG-driven insole development. Through the use of recycled materials—such as repurposed LCD glass—and low-carbon production processes, we help our partners meet sustainability goals without compromising product quality. Our ESG insole solutions are designed not only for comfort but also for compliance with global environmental standards.Flexible manufacturing OEM & ODM factory Taiwan
At GuangXin, we don’t just manufacture products—we create long-term value for your brand. Whether you're developing your first product line or scaling up globally, our flexible production capabilities and collaborative approach will help you go further, faster.Innovative insole ODM solutions factory in Taiwan
📩 Contact us today to learn how our insole OEM, pillow ODM, and graphene product design services can elevate your product offering—while aligning with the sustainability expectations of modern consumers.Innovative pillow ODM solution in Taiwan
Black cones show water molecules being oriented in the electric field at the interface with the lipid. Credit: Carlos Marques, ENS Lyon Electroporation studies reveal new insights into membrane pore dynamics and link lipid oxidation to aging and disease. Powerful electric fields have the ability to generate pores in biological membranes through a process called electroporation. Deliberately inducing these imperfections in membranes is a crucial technique not only in medicine and biotechnology but also in the treatment of food items. A Franco-German research team, headed by Dr. Carlos Marques from the Ecole Normale Supérieure in Lyon, France, and Prof. Dr. Jan Behrends from the Institute of Physiology at the University of Freiburg, has recently collected data that casts fundamental doubt on what has been accepted for decades as the standard model of this mechanism. “This is a challenge for theory building and numerical simulations in this field,” says Marques. The results have now been published in the Proceedings of the Academy of Sciences of the United States of America (PNAS). They could help to improve the transport of active substances in cells. Therapeutic Substances Enter Cells Through Electropores Direct current electric fields above a certain intensity disrupt the organization of lipids, fat-like molecules that form the basic structure of biological membranes in a bilayer, stacked together in a kind of liquid crystal. The resulting electropores, which are usually only stable for a very short time, allow water and solutes in the surrounding medium – such as drugs or other active substances, including RNA or DNA – to enter a cell. Since the bilayer of lipids is very thin, measuring only five-millionths of a millimeter, it is not necessary to apply very high voltages to generate very high field strengths (volts per meter). Thus, even at a voltage of 0.1 volts across the membrane, the field strength is 20 million volts per meter. In air, for example, spark discharge already occurs at three million volts per meter. However, it must be direct current voltage; alternating current fields in the megahertz-gigahertz range such as those generated by cell phones do not cause pores. While the technique is well established, there is still a need to optimize electroporation of cell membranes for various purposes, such as to introduce genetic material for gene therapy. For this purpose, it is important to understand precisely the mechanism of pore formation under electric fields. A Standard Model With Little Experimental Verification A standard theoretical model of electroporation from the 1970s assumes that the electric field applies pressure to the lipids, thereby increasing the probability of pore formation. So far, however, there is only little experimental verification of the model. This is due, first, to the difficulty of directly detecting the formation of electropores and, second, to the necessity of carrying out a very large number of such experiments in order to arrive at statistically tenable conclusions. This is because, in contrast to pores formed by proteins, electropores exhibit a very diverse, less stereotypical behavior. A method that is capable of detecting the formation of pores with great accuracy and high time resolution is the electrical measurement of ionic current. Ions are positively or negatively charged constituents of the salts present in all biological fluids and, thus, inside and outside the cell. They are practically incapable of penetrating intact membranes, but as soon as a pore is opened, they are transported through it in the electric field. This transport of charged particles can be measured with highly sensitive amplifiers as a tiny electric current of a few billionths to millionths of an ampere. For this purpose, artificial lipid bilayers are created in thin Teflon layers via tiny openings of around 0.1 millimeters in diameter and placed between two electrodes. This technique of membrane formation is highly susceptible to failure – only one membrane is formed at a time, which breaks easily, especially during tests with higher voltages. New Method for Creating Lipid Layers For their experiments, the research group used a microchip with many openings, through which significantly more stable lipid layers can be generated very quickly and repeatedly using simplified procedures. This so-called microelectrode cavity array (MECA) was developed by Jan Behrends’s research group and has been produced and made commercially available by the Freiburg start-up company Ionera Technologies GmbH founded in 2014. With the help of this device, it was now possible for the doctoral candidate Eulalie Lafarge from the Charles Sadron Institute at the University of Strasbourg and Dr. Ekaterina Zaitseva from the Freiburg research group to generate hundreds of membranes in a relatively short time and to measure and quantify pore formation as a function of the strength of the direct current field. The results demonstrated that, contrary to the prediction of the old standard model, the energy barrier for pore formation decreases not with the square of the field strength but proportionally to the field strength. In other words, doubling the field strength reduces the energy barrier only by half, not fourfold. This suggests a fundamentally different mechanism: a destabilization of the interface between lipid and water due to a reorientation of the water molecules in the electric field. Oxidized Membranes Also Studied This result was also confirmed for membranes whose lipids were oxidized to varying degrees. This is interesting because lipid oxidation is a natural process in the regulation of cell membrane function and plays a role in the natural aging of the organism and possibly also in diseases such as Parkinson’s and Alzheimer’s. “Particularly in view of the medical significance of this topic, we want to pursue it further, also including optical methods, in order to reach a real understanding of this important phenomenon,” says Behrends. Reference: “Activation energy for pore opening in lipid membranes under an electric field” by Eulalie J. Lafarge, Pierre Muller, André P. Schroder, Ekaterina Zaitseva, Jan C. Behrends and Carlos M. Marques, 7 March 2023, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.2213112120
Zoomed in detail of the Mandelbrot set, a famous fractal, at different spatial scales of 1x, 4x, 16x, and 64x (from left to right). Credit: Image by Jeremy R. Manning Understanding how the human brain produces complex thought is daunting given its intricacy and scale. The brain contains approximately 100 billion neurons that coordinate activity through 100 trillion connections, and those connections are organized into networks that are often similar from one person to the next. A Dartmouth study has found a new way to look at brain networks using the mathematical notion of fractals, to convey communication patterns between different brain regions as people listened to a short story. The results are published in Nature Communications. “To generate our thoughts, our brains create this amazing lightning storm of connection patterns,” said senior author Jeremy R. Manning, an assistant professor of psychological and brain sciences, and director of the Contextual Dynamics Lab at Dartmouth. “The patterns look beautiful, but they are also incredibly complicated. Our mathematical framework lets us quantify how those patterns relate at different scales, and how they change over time.” In the field of geometry, fractals are shapes that appear similar at different scales. Within a fractal, shapes and patterns are repeated in an infinite cascade, such as spirals comprised of smaller spirals that are in turn comprised of still-smaller spirals, and so on. Dartmouth’s study shows that brain networks organize in a similar way: patterns of brain interactions are mirrored simultaneously at different scales. When people engage in complex thoughts, their networks seem to spontaneously organize into fractal-like patterns. When those thoughts are disrupted, the fractal patterns become scrambled and lose their integrity. When people listen to a story, their brain network interactions organize into fractals. Small-scale (order 1 and 2) patterns involve auditory and processing areas (yellow). Larger scale (order 3) patterns tie in visual areas (blue). The largest-scale (order 4) interactions also tie in brain regions that support high-level cognition (pink) and cognitive control (green). The orange and cyan ovals denote groupings of low-level and high-level regions, respectively. Credit: Image by Jeremy R. Manning The researchers developed a mathematical framework that identifies similarities in network interactions at different scales or “orders.” When brain structures do not exhibit any consistent patterns of interaction, the team referred to this as a “zero-order” pattern. When individual pairs of brain structures interact, this is called a “first-order” pattern. “Second-order” patterns refer to similar patterns of interactions in different sets of brain structures, at different scales. When patterns of interaction become fractal— “first-order” or higher— the order denotes the number of times the patterns are repeated at different scales. The study shows that when people listened to an audio recording of a 10-minute story, their brain networks spontaneously organized into fourth-order network patterns. However, this organization was disrupted when people listened to altered versions of the recording. For example, when the story’s paragraphs were randomly shuffled, preserving some but not all of the story’s meaning, people’s brain networks displayed only second-order patterns. When every word of the story was shuffled, this disrupted all but the lowest level (zero-order) patterns. “The more finely the story was shuffled, the more the fractal structures of the network patterns were disrupted,” said first author Lucy Owen, a graduate student in psychological and brain sciences at Dartmouth. “Since the disruptions in those fractal patterns seemed directly linked with how well people could make sense of the story, this finding may provide clues about how our brain structures work together to understand what is happening in the narrative.” The fractal network patterns were surprisingly similar across people: patterns from one group could be used to accurately estimate what part of the story another group was listening to. The team also studied which brain structures were interacting to produce these fractal patterns. The results show that the smallest scale (first-order) interactions occurred in brain regions that process raw sounds. Second-order interactions linked these raw sounds with speech processing regions, and third-order interactions linked sound and speech areas with a network of visual processing regions. The largest-scale (fourth-order) interactions linked these auditory and visual sensory networks with brain structures that support high-level thinking. According to the researchers, when these networks organize at multiple scales, this may show how the brain processes raw sensory information into complex thought—from raw sounds, to speech, to visualization, to full-on understanding. The researchers’ computational framework can also be applied to areas beyond neuroscience and the team has already begun using an analogous approach to explore interactions in stock prices and animal migration patterns. Reference: “High-level cognition during story listening is reflected in high-order dynamic correlations in neural activity patterns” by Lucy L. W. Owen, Thomas H. Chang and Jeremy R. Manning, 30 September 2021, Nature Communications. DOI: 10.1038/s41467-021-25876-x
Five early Silurian fishes from China rewrite the evolutionary story of “from fish to human.” Credit: IVPP The Discovery of a Fossil “Treasure Hoard” Illuminates the Rise of Fishes Researchers from the Chinese Academy of Sciences‘ Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) have recently found two fossil repositories in the early Silurian strata of southwest Guizhou and Chongqing that are rewriting the “from fish to human” evolutionary story. Four different papers describing their findings were recently published in the journal Nature. Humans are one of the 99.8% of species of extant vertebrates that are gnathostomes, or jawed vertebrates. The basic body plan and several key organs of humans can be traced back to the origin of gnathostomes. One of the most significant developments in the evolution of vertebrates is the emergence of jaws. The Chongqing fish fossil depository is the world’s only early Silurian Lagerstätte which preserves complete, head-to-tail jawed fishes, providing a peerless chance to peek into the proliferating “dawn of fishes.” Credit: NICE Tech/ScienceApe However, how this innovation occurred remains a mystery, owing to the fact that fossils of early jawed vertebrates were not discovered in large numbers until the beginning of the Devonian (419 million years ago), despite molecular data indicating that the origin of jawed vertebrates should have occurred earlier than 450 million years ago. As a result, there is a significant gap in the fossil record of early jawed vertebrates, lasting at least 30 million years from the Late Ordovician to the Silurian. Silurian Fish Graphic. Credit: NICE Tech/ScienceApe The latest findings of Zhu Min’s team from IVPP are unearthed from two new fossil depositories, shedding light on the rise of jawed vertebrates: These jawed fishes were already thriving in the waters of the South China block, at least 440 million years ago, and by late Silurian, more diverse and larger jawed fishes had evolved and began to spread around the world, opening the saga of fish landing and our humans eventually evolved. Discoveries of fish fossils from the two depositories help to trace many human body structures back to ancient fishes, some 440 million years ago and fill some key gaps in the evolution of “from fish to human,” and provide further iron evidence to the evolutionary path. The Chongqing fish fossil depository in the Upper Red Beds of the Silurian system dates back to 436 million years ago. It is the world’s only early Silurian Lagerstätte (fossil depository with exceptional preservation) which preserves complete, head-to-tail jawed fishes, providing a peerless chance to peek into the proliferating “dawn of fishes”. This fossil “treasure hoard” stands among other great Chinese Lagerstätten: Chengjiang Biota and the Jehol Biota, all provide key jigsaw puzzles previously missing in the tree of life. References: “The oldest gnathostome teeth” by Plamen S. Andreev, Ivan J. Sansom, Qiang Li, Wenjin Zhao, Jianhua Wang, Chun-Chieh Wang, Lijian Peng, Liantao Jia, Tuo Qiao and Min Zhu, 28 September 2022, Nature. DOI: 10.1038/s41586-022-05166-2 “Galeaspid anatomy and the origin of vertebrate paired appendages” by Zhikun Gai, Qiang Li, Humberto G. Ferrón, Joseph N. Keating, Junqing Wang, Philip C. J. Donoghue and Min Zhu, 28 September 2022, Nature. DOI: 10.1038/s41586-022-04897-6 “Spiny chondrichthyan from the lower Silurian of South China” by Plamen S. Andreev, Ivan J. Sansom, Qiang Li, Wenjin Zhao, Jianhua Wang, Chun-Chieh Wang, Lijian Peng, Liantao Jia, Tuo Qiao and Min Zhu, 28 September 2022, Nature. DOI: 10.1038/s41586-022-05233-8 “The oldest complete jawed vertebrates from the early Silurian of China” by You-an Zhu, Qiang Li, Jing Lu, Yang Chen, Jianhua Wang, Zhikun Gai, Wenjin Zhao, Guangbiao Wei, Yilun Yu, Per E. Ahlberg and Min Zhu, 28 September 2022, Nature. DOI: 10.1038/s41586-022-05136-8 The study was funded by the Chinese Academy of Sciences.
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